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Results for "

hD4 receptor

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101065
    AJ-76 hydrochloride

    (+)-AJ 76 hydrochloride; (1S,2R)-AJ 76 hydrochloride
    AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pKi values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.
    AJ-76 hydrochloride
  • HY-101382
    GR 103691
    1 Publications Verification

    		 Dopamine Receptor Neurological Disease
    GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites .
    GR 103691
  • HY-101349A
    L 741742 hydrochloride

    		Dopamine Receptor Neurological Disease
    L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. L 741742 hydrochloride has a good brain penetration. L 741742 hydrochloride can be used in study nervous system disorders, particularly schizophrenia .
    L 741742 hydrochloride
  • HY-147398
    Dopamine D4 receptor antagonist-1

    		Dopamine Receptor Neurological Disease
    Dopamine D4 receptor antagonist-1 is a selective DRD4 antagonists, with a Ki of 9.0 nM for Hd4.2. Dopamine D4 receptor antagonist-1 can be used in study of schizophrenia .
    Dopamine D4 <em>receptor</em> antagonist-1
  • HY-W329175
    N-Despropyl Ropinirole

    SKF-104557

    		 Dopamine Receptor Neurological Disease
    N-Despropyl Ropinirole (SKF-104557) is an active metabolite of the dopamine D2 receptor agonist Ropinirole (HY-B0623). N-Despropyl Ropinirole is a full agonist at human D2 and D3 receptors. N-Despropyl Ropinirole is a partial agonistof the hD4 receptor .
    N-Despropyl Ropinirole
  • HY-14328
    Sonepiprazole

    PNU-101387G; U-101387G

    		 Dopamine Receptor Neurological Disease
    Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .
    Sonepiprazole
  • HY-B0623A
    Ropinirole hydrochloride
    1 Publications Verification

    SKF 101468 hydrochloride

    		 Dopamine Receptor Neurological Disease
    Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease .
    Ropinirole hydrochloride
  • HY-B0623
    Ropinirole

    SKF 101468

    		 Dopamine Receptor Neurological Disease
    Ropinirole (SKF 101468) is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole has no affinity for the D1 receptors. Ropinirole has the potential for Parkinson's disease .
    Ropinirole
  • HY-14327
    FAUC 213

    		Dopamine Receptor Neurological Disease
    FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. FAUC 213 has less activity on D2 and D3 receptors (Kis of 3.4 μM, 5.3 μM for hD2, hD3, respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic .
    FAUC 213
  • HY-B0623AS1
    Ropinirole-d7 hydrochloride

    SKF 101468-d7 hydrochloride

    		 Dopamine Receptor Neurological Disease
    Ropinirole-d7 (hydrochloride) is the deuterium labeled Ropinirole hydrochloride[1]. Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[2][3].
    Ropinirole-d7 hydrochloride
  • HY-B0623AS2
    Ropinirole-d3 hydrochloride

    SKF 101468-d3 hydrochloride

    		 Dopamine Receptor Neurological Disease
    Ropinirole-d3 (hydrochloride) is the deuterium labeled Ropinirole hydrochloride[1]. Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[2][3].
    Ropinirole-d3 hydrochloride
  • HY-B0623AS3
    Ropinirole-d14 hydrochloride

    SKF 101468-d14 hydrochloride

    		 Dopamine Receptor Isotope-Labeled Compounds Neurological Disease
    Ropinirole-d14 hydrochloride is deuterated labeled Ropinirole hydrochloride (HY-B0623A). Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease .
    Ropinirole-d14 hydrochloride

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